Mod Cooperative

Fellow panfandom mods! I have some questions for you. I'm looking for general opinions about activity in a fast paced, plot heavy panfandom setting for a large game (35+ players, 200+ characters). What kind of rules regarding activity do you think are fair? How do you go about enforcing them? When a player is not up to that activity requirement, how do you handle it? Do you have rules about hiatuses? How do they come into play when it comes time to check up on activity? Any opinions or just sharing how you've handled activity checks successfully in the past would be helpful to me! I'm just wondering if the way I handle it at my game is the best way or if there are other ways out there that might be better for myself and my players.

Thanks!!!