This is from World's Finest Comics #289. It's written by Doug Moench and illustrated by Adrian Gonzales. The cover is by Gil Kane.
Batman is upset when he is unable to save a mugging victim.
Meanwhile, Superman saves some rock climbers from getting flattened by a giant boulder. He overhears the climbers react in wonder, and feels depressed at how his world is destroyed and that he's alone.
Later in the batcave, a depressed Batman asks Alfred to leave him alone.