Maryanne hadn't been really aware of the red eyes. It was definitely a look. But she was aware of the Spiderman status. You don't live through something like killing Pennywise, and still hold a secret like that. She just hadn't paid much attention to the other Miguel's eye color.
She passed him the bottle so she could properly sign. "This is 'The Blue stuff'. I did bring you some Asgardian wine that you can take home, though. That stuff," She pointed at the bottle he was holding, "Could give either of us alcohol poisoning. And it's hard to come by, so I just brought the one bottle."