Spidey fights (and beats) Macendale Hobby after drinking spiked punch. Afterward he says 'Once I find out how I got this way I'll make sure it never happens again.' Now obviously he could mean 'never fight crime drunk again' rather than 'never drink again,' but considering he never knows WHEN he's going to be called upon to fight crime it seems silly that he'd knowingly get drunk to ease the 'pain' of talking to an ex, but eh...