You know, it seems that every time another company does a Fantastic Four pastiche, the spaceflight either goes horribly wrong or the group are evil. Planetary, Batman Beyond, Cyborg Superman. Sometimes even Marvel gets in on the act, in their more cynical What Ifs (Ruins, frex). In the Marvel Adventures universe, at least, the U-Foes got their powers by deliberately duplicating the FF's spaceflight, but they were arguably evil to begin with.