Having read Initiative from the start, I'll try clearing this up.
Komodo (Melati Kusuma) has always been missing her legs (she lost them in a car accident). Because of this, she studied to get taken on as a research assistant by Dr. Connors (I believe there's a panel of her working in the lab in a wheelchair). She worked out a revised version of the Lizard formula and used it to assume her Komod form, restoring her legs. In fact, Connors praises her to the Initiative staff at one point for improving his formula, removing the rampaging supervillain problem (though it only works for Melati).
This is why in issue #3 (I believe) she deperately begs War Machine not to use the SPIN tech on her, and why she's initially so upset that Hardball saw her untransformed state.