OMD is still a very controversial topic among Spider-Man fans, to the point where Marvel has banned people for discussing it on the message boards. Marvel knows this is a sensitive topic among fans.
Again, any sort of joke poking fun at the marriage is bound to get a negative reaction, and the writers know this. I'm hardly saying that this is an insult, but it is a little jab at the fans who miss the marriage. And my point was, the writers keep on acting shocked and defensive that OMD is still an issue with the fans two years later and they have no problem throwing in stuff like this.