Depends on what you mean by "traditionally", if you mean the Bram Stoker Dracula, then yes it was particularly the Christian symbology which warded him off, and Van Hesling makes a particular note that he has special dispensation from the Vatican to carry consecrated Communion wafers (Which is a tightly controlled privilege, granted to members of the clergy and Ministers of Commmunion).
If you mean other popular takes on the genre, like Salem's Lot, then it's the faith, not the symbol.