There is no cure for the age sickness my kind suffers from. Those that aren't dealt with quickly cause nothing but death and suffering. Leo was so desperate to save his mate he sent his moon and blood crazed wolf on a young woman to force a Change upon her. She survived the Change and became an Omega. Normally for us we can only really turn such a human if they are close to death, there's a compulsion to save them by whatever means. Thus the reason the crazed wolf was set on her. But because she was Omega and outside the pack structure, they abused her in every way to make her obey. It wasn't until the Marrok's enforcer Charles came that she was freed from three years of hell.
So yes. If Leo and Isabelle show up I will kill them and I won't lose any sleep over it.