Buffy offered the flask back to Spike after he was finished speaking, kind of like a prize for saying what was on his mind. They didn't always have frank talks like these, but when they did it was usually pretty eye opening and rewarding.
"It's like I don't even know the people I'm supposed to love anymore," she agreed. Not that Spike loved those people, but he knew what she meant. "And here we are just trying to find something to hold onto." She glanced at Spike, realizing what that might sound like, but quickly averted her eyes. "I don't know how you stand it."