Helena's in Foxtrot, but given the powers these two have, I'd love it if Nocturne and Reaper have gone on missions together in the past, and/or will in the future, because it's an awesome combination imo.
I also have two Alphas. The first is Blitz, Damage #1, and he's been in the program for a good while now. He's rooming with his brother. Blitz loves the ladies and will undoubtedly have hit on Nocturne in the past.
The other is Handler #1 (still figuring out her name). She wouldn't handle Nocturne directly, since her supers are the two tanks and the healer, but they will have interacted on some level at some point. No guarantees that it's been pleasant. :X