I was surprised and slightly depressed by ODD JOHN. Years of reading other science-fiction books like SLAN and Henry Kuttner's "Baldy" stories (not to mention Marvel Comic's X-MEN*) had led me to expect a tale of a noble young mutant unfairly oppressed by a heartless humanity and only fighting back when forced to. No such thing. John Wainright is, from a normal human viewpoint, a monster. From childhood on, he uses his enhanced intelligence and telepathic powers to manipulate and experiment on people with no regard for their welfare. This is more realistic, I suppose, than the altruistic supermen who fight for the mankind which scorns them, but it is unsettling to read unless you're expecting a horror story.
Aside from the policeman he cold-bloodedly stabs to death (the ten-year-old John had been committing burglaries in the neighborhood to gather some capital), our protagonist kills a number of people who get in his way, with no sign of remorse or regret. When he takes his motley crew of mutants to found their experimental colony in the South Pacific, they ruthlessly compel the natives already living on the island to climb up on a huge pyre and expire, their bodies burnt away. Just so these normal folk are not in the way of their betters.
John even makes a speech to his human follower "Fido", "Well, if we could wipe out your whole species, frankly we would. For if your species discovers us, and realizes at all what we are, it will certainly destroy us. And we know, you must remember, that Homo Sapiens has little more to contribute to the music of this planet, nothing in fact but vain repetition. It is time for finer instruments to take up the theme." And at that time, there has been no persecution of the mutants by normal people, who aren't even aware of their existence.
ODD JOHN does use "Homo Superior" extensively, predating Kuttner's brief mention of the phrase. So the line of influence here would be ODD JOHN to SLAN to the "Baldy" stories to THE X-MEN and all their dozens of spin-offs and imitators.