Archenemy
How about werecats? The idea may not be as well know as wolf people but the idea of people who transform into panthers or lions isn't completely unknown in pop culture. Plus having two groups with animalistic-humanistic societies would be interesting. It could be great seeing how they interact with each other and regular humans provided it had a good writer. I think the people who did the Gargoyles TV show could pull it off.
Darn it now I'm all excited about this idea and I doubt it will ever come to be. :(