It could, but I have feeling a relationship between Peter and Michelle will not be the case. There's always the possibility that nothing actually happened, that he was so drunk he fell asleep in the wrong bed, and this is just another embarrassing moment in the life of Peter Parker. But regardless of whether he had drunken sex with his roommate, Michelle, or not, the situation would be so awkward between them that it's conceivable that she throws him out or he moves out--since it's technically her apartment because she pays the rent--and Peter starts looking for a new place, on top of having to deal with his apparent drunken one-night stand AND the return of his ex-fiancee (at least according to BND) whom he still has feelings for. Also, Michelle's brother, Vin, is a cop, and can barely stand Peter enough as it is.