To the best of my knowledge, the French animated series was based on Le Nid, and the Disney animated was about yet another Marsupilami and his battles with a poacher. His kids and wife don't figure into the other two.
One assumes the marsupilami that Spirou & Fantasio had (it was more Fanta's pet than Spirou's really) was sent back to live in the wild, although it's not explicitly mentioned. When Franquin left the series he took the rights to his creation with him (thus the spin-off), and future creative teams weren't allowed to use it. Which is a pity in some ways, although I don't see how it would fit into modern era books in any case.