I suppose it could have Unfortunate Implications, but given that in a back-reference to Nite Owl they started having Ted wrestling with weight issues, it might be kind of funny to have girl!Ted checking out her hips in the mirror-- think kind of like Helen Parr in The Incredibles.
(And I could see some folks having fun writing a chunky, spunky girl!Ted. There were some pretty cute Rule 63 versions of Nite Owl, after all...)