Well, yes, it's hinted with all the subtlety of a sledgehammer that Mary Jane knows, but until the FF and the NuAvengers, Marvel editorial has REPEATEDLY stated that NO ONE knows, so ... yeah.
Then again, Marvel editorial had also insisted, to the point of INSULTING any readers who suggested otherwise, that NOTHING else but the marriage has changed, which would mean that Mary Jane got PREGNANT OUT OF WEDLOCK, and when Tom Brevoort was asked about this, his response was to insult the person asking the question, WITHOUT ANSWERING the question.
Of course, NOW, AFTER all of that, Quesada has said, "Oh, yeah, ONE OTHER thing DID change, and you'll find out what it was NEXT YEAR."