Why you don't mess with Sue Richards A little late for Mother's Day...
I don't remember the context, really, since it's been around sixteen years since I've read the story, but this exchange has never been far from my thoughts any time I've seen Sue since.
The mini-series had something to do with Doom being a dick and making like a good guy to the X-Men so they'd help defend him against the FF for...something. This is right at the end, after everything's settled, everyone's making their amends. All of them are a little tense to see Doom and Sue are chatting, expecting it to reopen the wound and start the big fight over again.
Sorry for the crooked scans. I read this story when I was a kid (it was probably at least five years old after it came out, because I'm not much older than it) and this part always stuck out with me because it's the first time I ever encountered a strong female character in comics. It kind of ingrained idea that Reed might be the smartest, Ben might be the strongest, and Johnny might be the funnest, but Sue is most certainly the most powerful of the Fantastic Four. She is no one to be trifled with, and definitely someone whose family you don't put in jeopardy. This blew my seven-year-old mind.