Doctor Poison looks fantastic. I was never fond of her earlier look, with the perma-grin that made her drool, the gimp-style mask and the black smock or whatever, because she never, ever looked like a viable threat for Diana, who could just loop the lasso around the dolt and that's it, problem solved.
This works so much better for me. The gas-mask brings some real scariness to the design, because you have no idea what she's going to look like underneath it, and the lack of an overcoat/smock/moo moo-thing makes her looks more mobile and more of a threat. I also like the subtle details on her body, and would love to find out what it means - tattoos? An infection?
Despite my concerns about that Supes/Diana set of panels, I'm actually more excited about Wednesday Comics than any of the other weekly-style books. Who knows, this might be the thing that gets me picking up monthly books again?