You know what's hilarious? There was an absolutely beautiful issue of Sensational Spider-man that came out right before One More Day started where Peter is moping around about Aunt May and all that when God HIMSELF comes to Peter in a human form and talks to him about all kinds of stuff like how it's Peter's role to be Spider-Man and he shows him a fraction of the thousands of people he's saved over the years. At the end, Peter asks God not to let his Aunt May die and God tells Peter to have faith and then disappears. The end of the issue showed a possible future with Peter and Mary Jane growing old together with their children Ben and Mary.
And then Peter went and made a deal with the devil. After God told him to have faith. Yup.