Aw, they could have been depressed puppers together... obviously not when they are puppers because I'm sure that part of them was running wild, free and ferocious. That's super shitty about his twin, though. That would be the worst. She'd not be able to relate, but she'd give him extra hugs when he wanted them.
She would love to have a place to run as long as he could assure her she couldn't escape and kill someone. She'd not exactly hate herself forever, because shit happens and she'd eventually come to terms, but she'd be super done for a while. Is there a pack?