my girl here is a hunter without a conscience - she's in town to take out any and all supes that she comes across, which will eventually get her killed i'm sure unless someone is able to talk some sense into her. the person that gets through to her could be human, another hunter, or even a supernatural themselves - i've left details pretty open for creativity here.
if that isn't of any interest, she can always use more allies, someone she butts heads against, or pretty much anything else!