"I'm not sure you and I need to go into the area of inappropriate questions. You might make me blush." That was said in the Derek dead pan expression and voice that Chris at least would know was him being joking and yet serious all at the same time. Derek really didn't want to know anything out loud about some people.
It was bad enough that he had senses that let him scent it and hear it all over the place. You got to be really good at tuning a lot of things out when you were a werewolf for your own sanity.