Someone or something has let a genie out of a bottle and it's granting our wishes, most likely some sort of minor-grade reality warp or maybe enchantment? Anyone in possession of magic beans? Either way: the connecting thread is desire.

Consider:

» All Billy wants is to be a real boy.
» Gale can't tell a lie, but is this Gale's wish or Dean's? Or mine, for that matter.
» Alec can't tell a lie either, wondering if it's subconscious desire or someone else again?
» Astrid and Bex and Alex have all lost their problematic powers.
» Pella's shut-in, socially awkward brother has suddenly become charming.
» Pella herself is a shut-in, socially awkward serial killer... still, but apparently she's younger, so maybe she wanted to get rid of those fine lines around her eyes.
» Ash is suddenly pop-culture savvy, which means maybe one of these days he'll admit that crazy angel cults are, in fact, bullshit.
» Steven is sent back to a time before SHIELD destroyed him.
» Luka wants Steven's memories back, and he receives them - just not where he wants them.
» And so forth

Since we've all gotten what we wished for, I propose that we sit on our hands and do freaking nothing, because this is great.