Very interesting! And, with the clone evolution techniques, the earlier "flawed" clones could start to be chased down/hide/join the resistence, too. And, maybe like on I Robot, clones could start rebelling within their own kind.
Also, I think it would be interesting to make up "corporations" behind each group, that would sponsor their missions, since it would take a lot of money to go from one place to another, spanning even from country to country.
Would the time setting be primarily contemporary or in the future?