[Those words hurt in some deep part of him that Itachi locks away and refuses to acknowledge. Itachi isn't surprised by Sasuke's anger. How could his brother not be angry with all that he has done to him?
And he knows from Sasuke's words before that he had planned to attack Konoha. That his brother had chosen to do things his own way instead of accepting Itachi's decisions.
Sasuke had never been one to do just as others wanted of him.
He fully turns around and steps back toward his brother, able to sense his chakra even without his sharingan. His greyed eyes look down at him, his head tilted lightly and his face a mask of apathy.]
That wasn't what I asked, little brother. I asked if you would know what to do if you had that power over me.