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[Making people comfortable talking to him is one of the Doctor's talents, although it can easily go the other way, where people are in fact terrified of him. There's no need for Marie to be intimidated by him just now, though.]
I have, yes. [He smiles, and there's something sad about the expression.] I've lived a very long time, and I've known some brilliant people and seen some amazing things. It's difficult not to be in love when you've done that.