Time Lords don't use 'em. Well...the Doctor's the last Time Lord but they had TARDIS so they didn't need manipulators. Other species tend to use 'em and they muck things up by not knowin' what's fixed and what's changeable.
[Always!] Time And Relative Dimensions In Space. Sentient space and time machine. She's brilliant. Guess she's a ship that's psychically linked to the Doctor.