[Video]
Beheading. Fire. Sunlight. A wooden stake through the heart. Holy symbols. Water. Garlic. [There are more, many of them methods that were well-documented in the old days, before the cataclysm and the rule of Dracula, but lost to the humans of D's time over millenia of subjugation and careful conditioning imparted by their vampire masters to render the human "livestock" less of a threat.]