I believe right now the Pepper play is interested in starting out the romance, as she came in without a Tony around. I'm going to direct her here though, so that you can brainstorm that out.
As for a Natalia, we currently don't have one (but that doesn't mean I don't have enough characters as is...)
Unfortunately, we have a serious lack of villains. Most are NPCed, but we did have a Doom for a while so someone could possibly take up the mantel again. At the moment, most of the evil-doers are just Brotherhood members of misc characters.
While NPCing can be a bit lame at times, we do have a lot of people who are willing to play along for some awesome plot, so if Doom was needed, I'm sure we could work something out without much of a problem.