In the year 2000, Charles Xavier opened the doors to his School for Gifted Youngsters. Mutants. Now, fifteen years later, much has changed. Xavier is on Muir Island, rumored to be establishing a second school for mutants, while much of his original first class have seemingly disappeared; only the X-Men know that their mission is to travel through time and space to try and stop the evils that have been enacted on their own world.

Former students and current X-Men have taken the reins from the old guard and are finding that now there are new horrors awaiting them. And new fights for students, residents, and humans alike to face.