ISO a male best friend for a PSL, ignore face or don't, I can play older faces if you want a longer history between them:
They have been best friends since high school/college and she's always been there while he's struggled with his mental health. They either dated, married, or had a baby a few years ago. Things didn't work out, he either was having a hard time with his medications or symptoms, or was misdiagnosed to start out with, and they ultimately split, but years later, they're starting to take baby steps toward getting back together.