The more I think about it, the more I dig the idea of stranding a couple of characters somewhere populated by mythical beasts. Even better if they enjoyed a degree of power and influence previously (like the officer and the lawyer), that is stripped away by their circumstances. Developing skills over time is more fun IMO than the New Game+ versions where everyone is conspicuously well geared and trained to handle anything that comes their way ;)
So maybe something like Gilligan's Island, but spookier? Which isn't to say I'm opposed to the hilarity of creating a coconut radio. A good mix of horror and humor is my jam.