I'm comfortable enough in my heterosexuality to say that Muscular!Otto is a fine catch.
Then again, I always liked the idea that Otto genuinely did love May.
Really, Otto SHOULD be seen as Peter's PRIMARY archenemy, instead of Norman, because even more than Eddie Brock and Venom, Otto Octavius was always kind of Peter Parker Gone Wrong (ie. the science nerd who DIDN'T have an Aunt May or Uncle Ben in his life, to give him that sense of right and wrong).
It's a shame that they've bungled his childhood origins so many times (Zeb Wells' Norman Bates-ripoff interpretation of Otto was the WORST).