"Insane? No, I'm perfectly sane. I'm one of the few willing to make sacrifices for this small world of ours." Stryker genuinely believes it too, that mutants are to be used and contained, information like the Doctor's Tardis should be in the hands of the government, etc.
Kurt holds him fast from behind, not letting him go.
"Come now, Doctor, was it?" As if Stryker was trying to coax a child to do something difficult. "Either you tell me or we do this the hard way. Starting with finding out if our special serum works on you as well as it does on our friend Kurt here." He indicates the blue man behind the Doctor.