It's apparent what the drug does now and the Doctor finds himself cursing the fact he'd turned his back on the other man. For all that he may be behind the drug, it seems to be drowned out at the moment.
He pulls against the other's grip, the knife at his throat not seeming to phase him as greatly this time around. He's not backing down, not when the man in charge is right before him. He pauses at the question however, raising a brow.
"You really think I'd help you? You really are insane aren't you?", he asked calmly, looking back to the men outside. "You can try all you'd like, but you'll never get it open. That's the only answer you're getting from me."