Oh but River loved being handcuffed, even if it wasn't to another person. When Rory came out all dressed in blue, she couldn't help but laugh a little. "I can't imagine what Mum ever saw in you," she teased.
Plus she'd probably seen worse. Um not that they knew about the whole Mels thing. Did they?
In any case, she headed with the rest of them out of the TARDIS and off to find the Doctor.