"Well, we find ourselves among monsters and magicians now. We've kept worse company." She smiled softly, lips pulled to the side to betray her own humor. It was clear she didn't believe that this person was actually magical, but since she didn't know enough to tell what Simon might actually be referring to, it was safest to play along. She was nervous and when Inara was nervous, she forged ahead. Projected confidence was the best palliative for anxiety.
"It's good to know that you're among peers. From what you've described, I can't imagine there's much here in the way of medicines that we're used to." Dipping a toe in the water.