Frye Twins
da Vinci did more for advancements in art and medicine and technology than can be measured; of course there was a sodding movement to get rid of him. Disgusting. Anyone different enough... but sure, I'll give you that they were a little more organised in how they did back in Ezio's time.
You wouldn't be encouraging this line of thought if you didn't know there was a chance. I'm the risk-taking romantic, not you. Generally.