No, there was nothing friendly about that half smile at all. Though, honestly, if Fred was truly trying to intimidate Connor then he would. However, he's keeping an eye on the good doctor just in case something goes wrong. It had better not, either.
Jughead looks over towards the doctor and barely even holds his head up before pulling the pillow down over his head. So, he doesn't see Fred move closer to the good doctor. All he wanted to do was sleep. He just wanted to go back to being warm too.