Hello, Angeli, I'm Jamie and I have Scorpius Malfoy here.
Scorpius probably knew Amber, since they were in the same house and same "blood circle," if not the same year at school. Scorpius was probably fairly familiar with all the Slytherins, but I doubt he kept in contact once he flew the coop, having been pretty engaged in his work since graduation. However, since Amber also works in the Ministry, albeit at a different department, it's possible they've seen each other since then. Scorpius would perhaps treat Amber as if he might enjoy patting her on the head like a trusty dog.
As for Dom, it's probably not too likely that they know one another formally, unless you have a reason that they might (although Scorpius is pretty well-inundated with Weasleys already), but it's likely that Scorpius reads her column and probably knows her from that. Don't judge him.
If you have any ideas and want to work something out, just let me know!