Promethea: Goes both ways
Here's an interesting panel layout trick, courtesy of Alan Moore and J.H. Williams III. In this two-spread, the panels can be read either clockwise or counterclockwise, and in either direction they'll make sense as a sequence and conversation.
I've also included the panels both immediately before and after the spread, so you can see what the conversation is coming out of and what it's going into, for proper context.