Okay... now, judging from my older predictions and how they fit current chapters (including this), I have some predictions to make:
Sasuke will join Akatsuki, blaming Konoha for killing Itachi and the clan.
He will also be charged with Itachi's Kyuubi responsibilities.
Most of the manga will henceforth focus on Team Kakashi racing Akatsuki across the world to different bijuu.
It will all climax in an epic battle between Sasuke and Naruto. (Optionally, fighting between Konoha+allies and Akatsuki+bijuu in background)
...And now the predictions go two ways, which I like to name "Sasuke Dies" and "Naruto Dies".
"Sasuke Dies" Scenario: After battle, Sasuke is dead. Naruto becomes Hokage, marries Sakura/Hinata and they have some nostalgic meeting at the memorial where Itachi's and Sasuke's names have been carved despite being hated missing nin.
"Naruto Dies" Scenario: After battle, Naruto is dead. Sasuke is forgiven and returns to Konoha, marries Sakura/Karin and starts reviving the clan by having lots of Sharingan wielding brats named Itachi, Naruto and whoever else they would like to name them after. Ends with Naruto II proclaiming that he will be Hokage or something like that.
THE END
I hope that I'm wrong. For my own sanity I hope I am, because I want Inner Sakura to at least ONCE smack a Tsukuyomi-user over the head.