[While he's never been hunted, there are certainly those who don't like him in the slightest. For the to-be president of the entire of the Hunters' Association to also be a vampire? It's an obvious given that the majority aren't very happy.
Not that Zero can blame them at all. His mentor and former guardian, the current President (and self-proclaimed adopted father of both he and Yuuki), his work partner and close friend, and a small handful of others are pretty much the only ones who are supportive.]