That softly condescending attitude immediately puts his back up, but he tries to get past it as best he can because, disguised as banter or not, this is probably the single most informative few minutes he's had since he arrived in the dome and he doesn't want to blow it.
He studies her for a moment. "Do you really believe that yourself? Or is it just another game, to try and get us to believe it?"
His instinct is still that this is all either just one big game to them, or an experiment. Or both, of course.