River didn't want to take his hand. She wanted to stay where she was, but it wasn't really an option. Simon had dragged her to the medical bay in Serenity on more than one occasion. He had her stay in there and rest near him while on medications. She tried to think of her brother, though it didn't work too well.
Still, she took his hand and got up with no real effort on her part. Actually coming out of the closet was another matter. She continued shivering a little, and swayed a little once on her feet. "Not - not safe without help. It won't stop. Don't want to get triggered. Wouldn't help, anyhow. Don't want it."