Rebellion is the easiest to use, and my fav for Dante in 4, but I really like Cerberus and Agni & Rudra I haven't had a chance to fight properly with Nevan but she wins major points for being a guitar! XD (And Dante isn't losing any of his weapon-sexual points)
Dang, Trish was going to have some fun at Nero's expense. I'll just I'll have to come up with something else.