Lotte would be the quiet girl in the theater department who is far too jumpy about everything. She'd also be on a scholarship, rumors would be going around about her sleeping with someone she's only friends with *cough*, and she's debating dropping out.
Joss is your resident party-hardy. Not that different from reality.
Xavier would have been screwed over by Lucas in his freshman year and come back in only a few years to enact revenge. As a TA obviously - using his powers or other things, he'd look older and stuff. Clearly he would also seduce Gina away from Lucas as well because LOVE AFFAIRS ARE BETTER IN COLLEGE SETTINGS.
Luther would be a security guard on campus. Don't mess with him, kids. :|