It was good to see fresh D/M show up in the Christmas challenge and the recent Remix Redux. It's still my favorite pairing to read, but (and I feel a little guilty about this), it's not my favorite to write. If I have an OTP to write now, it's Darius/Methos. And, you know, Roger and the others -- but that will all come around to D/M eventually.
A couple of years ago, Kronos/Methos was the hot OTP that a number of new writers picked up on their entry to the fandom, before tossing them aside and moving out. You rarely see Kronos stories these days, outside of drabbles or lannamichaels's wonderful things.