As the unofficial spokeswoman of the GFL, lemme hit you up with some answers.
1. All you have to do is send something to the league saying that you're interested. Coaches will be in touch if they're looking to sign you. Don't be afraid to tell them reasons they might be interested in you.
2. Yes, both genders can play. All players wear armored uniforms that essentially keep everyone at moderately similar power levels, so that people aren't getting killed out there.